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How does the antibacterial activity work in Manuka Honey?

The antibacterial activity in Manuka Honey is due to four major processes or qualities: the osmotic effect, the acidity of honey, the production of hydrogen peroxide in honey and the phytochemical factor.

1. The Osmotic Effect: Honey consists of 84% fructose and glucose and 15-21% water. The sugar molecules and the water molecules interact strongly. When the sugar content of honey is high and the moisture content (water) is low, bacteria can not grow in honey. Bacteria thrive in honey that has been either pasteurized or diluted with water, such as imported Chinese Honey, typically used in US bakeries as sugar coating.

2. Acidity: Honey has a pH between 3.2 and 4.5 and is considered quite acidic. The acidity inhibits the growth of bacteria. The optimum pH for bacterial growth lies between 7.2 and 7.4. However, if honey is diluted, the pH could become higher, and therefore the antibacterial quality of honey would be destroyed. Paradoxically, dilution is what is needed in order to support the production of the next important antibacterial component in honey: hydrogen peroxide.

3. Hydrogen Peroxide: This antibacterial component is encymically produced in honey through dilution. Hydrogen peroxide is considered to be the most important antibacterial component of honey. The concentration of hydrogen peroxide in honey is low enough not to inflammate a wound or damage the tissue.

4. Phytochemical Factors: Besides honey's strongest anti-bacterial component (hydrogen peroxide), honey also contains some minor chemical factors of that quality. Exactly here lies the difference between the antibacterial qualities of Manuka Honey and regular honey!
Manuka Honey from New Zealand has shown to have a unique phytochemical factor. What exactly the factor is has still not been identified yet. The factor was discovered 20 years ago by Prof. Dr. Peter Molan, Senior Lecturer Biochemistry at the Waikato University in New Zealand. Dr. Molan removed the hydrogen peroxide from Manuka Honey and could still observe a high antibacterial activity. In fact, hydrogen peroxide and the special antibacterial factor in Manuka Honey enhance each other's power through a synergetic effect. Manuka Honey is considered the most unique honey in the world today, because of its unique medicinal properties. The special antibacterial factor is also very stable: hydrogen peroxide, which most honeys contain, is easily destroyed by heat, light, water or the catalase effect of the body serum. The unique manuka factor (UMF), however stays in the honey and does not lose its antibacterial strength.

Manuka Honey has medicinal qualities not found in other honeys. Manuka Honey seems to have the ability to naturally destroy staph aureus and streptococcus pyogenes. Staph and strep bacteria are typically associated to the common cold, sore throat, strep throat and tonsillitis.

 


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